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Appendix Appendix Search Formulae (July 2020) MEDLINE (PubMed) Keywords: smoking, tobacco, smoking prevention, smoking cessation, smoking cessation aid, nicotine, tobacco use disorder, analgesia, analgesic, and pain. Literature search was conducted in July 2020 using the following formulae: Rights and permissions This article is published under an open access license

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The FDA also may withdraw the current order if its no longer expected to benefit the health of the population as a whole, such as if former smokers or young people use the cigarettes, or if theres a decrease in the number of current smokers who completely switch to VLN cigarettes, according to the FDA.

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