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In addition, nicotine boosts endogenous dopamine levels

Additional information This article is part of the Topical Collection on Rheumatoid Arthritis Rights and permissions About this article Cite this article Sparks, J.A., Karlson, E.W

He speaks swiftly but softly, and appears persistently anxious to make himself clear

In an important study by Khokhar and Tyndale, the authors found that 7 days of nicotine treatment increased CYP2B expression in the brain, but not liver, and surprisingly, this change in metabolism was sufficient to potentiate the sleep-inducing effects of the general anesthetic propofol in male rats (167)