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Previously, an abrupt shift to VLNC was associated with a significant increase in these beneficial health effects compared to attempts to gradually reduce NNC cigarette use

Theyre usually slower to take effect and can also last longer than you might want

Smokers who delay quitting by using smokeless products between cigarettes greatly increase their risk of lung cancer

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Standardization then requires conducting a series of blocks of regimented puffs (all with same puff duration and puff volume) varying different parameters to test the equilibrium between physical processes (figure 1) and considering the inter-parameter relations in figures 2-4