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In mature, middle root parts, both NtZIP4 and NtZIP5 participate in the uptake of metals from the soil solution (expression in the epidermis), but NtZIP4 plays a more universal role, as its expression can be found not only in the epidermis but also in other tissues such as the cortex and the central cylinder

On the patient side, limited understanding of what constitutes problematic drinking and attitudes towards seeking treatment can hinder recognition of need for help

Through these interactions, providers can advise smokers to quit, discuss appropriate treatments (e.g., medications and counseling), and provide referrals to quitlines or other community programs