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Some premium brands also use strong rigid style packaging to create a more high end appearance

And that Harvard chemist on the surgeon general's panel who smoked four packs a day was diagnosed with lung cancer within a year of the 1964 report, and died of the disease.

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Another limitation is that the study did not account for potential confounding factors such as lifestyle behaviours (such as coffee and alcohol consumption and physical activity), which may be associated with e-cigarette use

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