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A chronic whole cigarette smoke extract model reveals redoxmitochondrial adaptation in human lung epithelial and organoid models Experimental & Molecular Medicine Cigarette smoke contains more than 7,000 chemicals, and hundreds of them can harm the body. Some of the most well known include: Carbon monoxide reduces oxygen in the blood 12.4 Emissions from tobacco products Tobacco in Australia A next generation system for smoke inhalation integrated with a breathing lung on chip to model human lung responses to cigarette exposure Scientific Reports Cigarette Smoking and Inflammation: Cellular and Molecular Mechanisms PMC

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