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In 2014, the Food and Drug Administration funded 14 research centers nationwide, including Ohio State Universitys Center of Excellence in Regulatory Tobacco Science (the FDA funding ended in 2018 and it has been renamed the Center for the Advancement of Tobacco Science

Cons: Slower ramp-up time compared to other metals

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But, the standards in the industry have been significantly raised over time, and even cheaper brands [nowadays] often perform as good in those quality attributes during blind tests