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5B, pathway enrichment analysis using the 1238 metabolic features from cluster 7 generated eight pathways including N -glycan biosynthesis ( p = 0.012), porphyrin metabolism ( p = 0.015), glycosphingolipid biosynthesis ( p = 0.02), bile acid biosynthesis ( p = 0.022), leukotriene metabolism ( p = 0.031), prostaglandin formation ( p = 0.031), blood group biosynthesis ( p = 0.031), and arachidonic acid metabolism ( p = 0.034)

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24-month effect of smoking cessation on cognitive function and brain structure in later life