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However, studies using mouse models suggest that targeting mutant p53 might only be beneficial to patients with late-stage lung cancer, as mutant p53 proteins are only adequately activated in advanced tumours [154, 156]

Complications such as premature birth, stillbirth, a low birth weight baby, or even miscarriages are caused by smoking during pregnancy and put the mothers health at risk as well as the health of the unborn baby

The inhalators do not have an atomiser and the liquid nicotine concentration is 15 mg/ml

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16 If an adolescent is ready to quit, nonpharmacologic behavioral modification should be initiated immediately