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References Arajo MCB, Costa MF (2019) A critical review of the issue of cigarette butt pollution in coastal environments

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Liver enzymes, specifically those in the cytochrome P450 family, break down HHC into several metabolites, including 11-hydroxy-hexahydrocannabinol (11-OH-HHC) and 11-nor-9-carboxy-hexahydrocannabinol (HHC-COOH).** These metabolites mirror the metabolic pathway of Delta-9 THC, with 11-OH-HHC being the primary active metabolite responsible for THC-like effects