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The human cytochrome Cyp1a2 gene contains regulatory elements responsive to 3-Methylcholanthrene

The presence of cigarette smoke increases the risk of bronchitis, pneumonia, and lung cancer

Gum diseases Generally, majority of gum diseases is due to nicotine exposure from tobacco use

In 1890, cigarettes were an insignificant portion of the American tobacco market, especially compared with cigars, chew, and pipes