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Macrophages pigmented smokers macrophages in respiratory bronchioles and neighbouring alveoli, containing granular, yellow-brown cytoplasmic pigments References and Links Barnes P , Mechanisms in COPD compared with asthma semantic Scholar Benjamin, R MD, MBA VADM, USPHS, Surgeon GeneralExposure to Tobacco Smoke Causes Immediate Damage: A Report of the Surgeon General Bohadana A et al Mechanisms of chronic airway obstruction in smokers Respiratory Medicine Volume 98, Issue 2, February 2004, Pages 139-151 TCV

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Vaping THC California was the first state to legalize medical marijuana, in 1996, followed by over 30 states in the following two decades or so

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