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American Spirit has no affiliation with any American Indian or Alaska Native tribes, however its depiction of an American Indian warrior, peace pipe, and thunderbird on its cigarette packaging caused 65% of participants in a study to believe the brand had tribal affiliations, which was associated with perceptions of decreased harm and greater intentions to purchase

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The first group contains 100% pure Virginia tobaccos, meaning that the whole leaves are used as wrapper leaves and the leaves with small imperfections are used as the inlay

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