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Figure 1-4 reveals that between 1985 and 2003, smoking initiation rates among young adults increased 4.3 percent, from 64.7 per 1,000 individuals to 67.5 per 1000 (SAMHSA 2005)

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Breaking Down the Nicotine Dependency Cycle Your brains nicotinic receptors rapidly adapt to chronic nicotine exposure through a process called upregulation , where receptor density increases while sensitivity to natural rewards decreases

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