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This is consistent with the incentive-sensitization theory of addiction 4, 5 , which proposes that neutral stimuli can promote drug-seeking behaviour through association with drug effects, and that this is mediated through sensitization of particular brain systems, principally the ventral striatum

1 The prevalence has decreased slightly over the past several years

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Subapriya, R., Thangavelu, A., Mathavan, B., Ramachandran, C

To test this hypothesis, the CRC group and adenoma group were individually split into two enterotypes (referred to as subgroups) by employing the Dirichlet multinomial mixture model according to their gut microbiota composition