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Here are the cigar types with the mean nicotine concentrations for each, compared to cigarettes: Cigarettes 19.2 milligrams per gram of tobacco Large cigars 15.4 mg/g Cigarillos 13.0 mg/g Little cigars 12.6 mg/g Mini-cigarillos 12.5 mg/g Pipe tobacco cigars 8.79 mg/g Even cigars that contain as much or nearly as much nicotine as cigarettes probably don't deliver it as effectively to the smoker

4, Weir et al

[50] isolated DNA from the lung tissue of eight non-smokers, eight current smokers, and eight patients with COPD and confirmed the presence of high DNA methylation in smokers and patients with COPD compared with non-smokers

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Arimilli S, Damratoski BE, G LP (2015)