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Researchers continued to see the above results after controlling for education level and Fagerstrom Test for Cigarette Dependence baseline scores, with similar quit rates between e-cigarette users and varenicline users (absolute risk reduction, 1.47%

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Together with the estimation that mutation rate has zero narrow-sense heritability ( h 2 ), their findings suggest that the environment, including lifestyle factors, may play a bigger role in modulating the mutation rate/pattern than previously appreciated [275]

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