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48 Concurrently, cigarette manufacturers were seeking to reassure their customers that their products were safe, that if hazardous compounds were identified they would be removed, and that product modifications could help to reduce risks

For example, a retrospective cohort study by Crane et al

The primary data source for this indicator is the World Health Organizations (WHO) Global Health Observatory, with data harmonized to adjust for differences in age structure across populations

Although we cannot conclude that the mucosal changes were entirely from Swedish snus use, we can say that tobacco use (Swedish snus and other smokeless tobacco products) is a risk factor for developing mucosal changes