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Despite widespread awareness, millions of individuals continue to use tobacco in various forms, including smoking and smokeless products

These limitations underscore the need for a next-generation lung-on-chip system like CFAX12, which can more accurately replicate alveolar microenvironments and assess cigarette smoke toxicity in a reproducible and physiologically relevant manner

Once again, Villanelle knows her target

"Nicotine is a metabolic stimulant (speeds up metabolism) and an appetite suppressant (makes people feel less hungry)," said lead author Susan Veldheer of Penn State College of Medicine in Hershey, Pennsylvania, in an email

Numerous other consumers have raised similar complaints online, highlighting the prevalence of this issue