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These two MAPKs are known to be involved in MMP transcription by activating protein-1 (AP-1), a transcription factor predominantly resulting from the formation of a heterodimer between c-jun and c-Fos and mediating the regulation of several genes in response to various stimuli, including growth factors and cytokines 50

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In 2009 the National Enquirer printed a cover showing a very thin Swayze, with a story implying that he was close to death and nearing the end of his cancer battle