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This leads to a considerably higher likelihood of smokers developing: Studies indicate that the likelihood of smokers developing chronic sinusitis is 23 times greater than that of non-smokers

In these situations, geographically weighted regression (GWR) models can be useful for dealing with the spatial autocorrelation and multicollinearity of variables [80]

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For example, low CTR1 expression, as well as high ATP7A expression, are associated with poor platinum-based chemotherapy outcomes 49,50 , while high CTR1 expression correlates with longer progression free survival and overall survival after platinum-based regimens 61,69