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What nicotine does to your brain Nicotine addiction starts fast. When someone smokes a cigarette, nicotine goes into the lungs and quickly enters the bloodstream. It reaches the brain in just 720 seconds. Once there, it releases dopamine Smoking found to significantly increase the risk of depression Do Smoking and Nicotine Cause Headaches and Migraines? NHI do cigarettes increase serotonin The Link Between Smoking Cessation and Mental Health
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