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Like many in the business, he worries the new rules may even force him to shut down, putting him out of work

Staining tends to concentrate in areas where smoke contacts teeth the most: the front teeth, the tongue side of lower front teeth, and around the edges of old fillings or crowns where the surface is rougher

Discussion Given the critical role of mitochondrial function in the pathophysiology of COPD and its reported association with nDNA methylation, we set out to explore the effect of cigarette smoke exposure on DNA methylation of the mitochondrial genome