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From 2010 to 2015, US dollar-store sales grew to $45.3 billion from $30.4 billion, and hundreds of stores have opened

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Over time, the brain adapts by: Reducing natural dopamine production Requiring higher doses of nicotine to feel the same effects Increasing cravings and irritability without nicotine The National Institute on Drug Abuse (NIDA) reports that nicotine produces addiction-related brain changes comparable to other highly addictive substances, helping explain why quitting can feel difficult even after relatively short-term use

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But only 4 percent of these kids got their nicotine solely from cigarettes