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A pharmacokinetic study showed that TS increased clearance of olanzapine by 23% because of the induction of CYP1A2 enzyme activity in the liver (Callaghan et al., 1999)

Today, only two types of tobacco from numerous varieties are commercially cultivated

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Tobacco exposure is the leading cause of lung cancer, despite differences in the intensity of smoking and the type of cigarettes, and ~90% of lung cancers are attributed to smoking [2]