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Master Settlement Agreement On November 16, 1998, 46 State attorneys general and the major cigarette/smokeless tobacco product manufacturers signed a Master Settlement Agreement (MSA) to reimburse States for the cost of treating smoking-related illnesses

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To investigate the respiratory effects of PG and VG aerosol exposure, Boulay and colleagues at the Quebec Heart and Lung Institute conducted a randomized crossover, placebo-controlled study on the acute effect of nicotine- and flavor-free e-cig aerosol (70% PG, 30% VG) inhalation in healthy ( n = 20) and asthmatic ( n = 10) volunteers [24]