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It inhibits the activity of two key bacterial enzymes, DNA gyrase and topoisomerase IV, which are type II topoisomerases essential for DNA replication, transcription, repair, and recombination (Fish and Chow, 1997)

To clarify the effectiveness of tobacco weight reduction through decreased circumference on yields of individual sidestream smoke constituents, three 1-mg ISO tar yield ECs (K111, D111 and S111) were manufactured that differed in circumference, but maintained the same 1-mg ISO tar yield, tobacco blend and cigarette design (other than changes in filter pressure drop and paper permeability necessary to achieve the same ISO tar yield across the three cigarettes

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Effects of fetal exposure to heat-not-burn tobacco on testicular function in male offspring

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