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1 Nortriptyline is also effective, other antidepressants not so much A Cochrane systematic review of 10 antidepressants used for smoking cessation included 64 placebo-controlled trials, measuring at least 6-month abstinence rates as primary outcomes, and monitoring biochemical markers (such as breath carbon monoxide and urinary cotinine) to verify abstinence

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Spud brand menthol cigarettes became the fifth most popular brand in the US by 1932, [3] and it remained the only menthol cigarette on the market until the Brown & Williamson Tobacco Company created the Kool brand in 1933