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In response to the increased understanding that smoking causes lung cancer in the 1950s, tobacco companies made what appeared to be genuine efforts to reduce the danger of cigarettes by introducing filters to the majority of products

begins to morph into the self-centered, unmotivated dad as described by Sheldon and Mary in the Big Bang Theory

Phillips explains that the head of Japanese intelligence in Manchuria, General Kenji Doihara, spearheaded the opium-laced cigarette program by distributing them to warlords throughout China

Responding to email enquiries, Dr Luik said: "I always find it interesting that the only issue in which ad hominem attacks are raised is the tobacco issue and from the anti-tobacco movement

Written by Dan Aykroyd and John Landis