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Keywords: smoking cessation, electronic cigarette, COPD, tobacco harm reduction Introduction Smoking is an important cause of avoidable premature mortality globally, mainly due to lung cancer, acute fatal complications of atherosclerotic cardiovascular disease, and chronic obstructive pulmonary disease (COPD)

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By making science fair game in the battle of public relations, the tobacco industry set a destructive precedent that would affect the future debate on subjects ranging from global warming to intelligent design

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