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465 The anterior cingulate cortex, essential for emotional pain processing, shows increased blood flow in patients with PDPN, a hyperperfusion state that normalizes following duloxetine treatment

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3.7 Mitochondrial dynamics imbalance Mitochondrial dynamics involves the continuous fusion and fission processes that mitochondria undergo to regulate the shape, number, and distribution

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These nanovesicles act as high-speed delivery messengers