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Nicotine exposure was essentially non-existent

Wait to light up from, say the time you get in the car until you get to work before you light up, or from the time you wake up until after your coffee or breakfast

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In these models, active smoking in human subjects is reproduced by exposing animals to cigarette smoke collected at the filter end of the cigarette (mainstream smoke), whereas passive smoking is mimicked by exposing animals to environmental smoke from the lit end of a smoldering cigarette (sidestream component)

Be sure to include a due date for compliance to the new terms as well as an enforcement strategy