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Due to the large percentage of women utilizing nicotine products during pregnancy in the United States and globally, this review seeks to centralize pre-clinical and clinical studies focused on the neurobehavioral and neurodevelopmental complications associated with prenatal nicotine exposure (PNE) such as alterations to the hypothalamic-pituitary-adrenal (HPA) axis and brain regions such as the prefrontal cortex (PFC), ventral tegmental area (VTA), nucleus accumbens (NA), hippocampus, and caudate as well as changes to nAChR and cholinergic receptor signaling, long-term drug seeking behavior following PNE, and other related developmental disorders

Cambridge, MA: University of Chicago Press

Il sadresse tous les fumeurs, mme en cas de cancer

Sadly, similar conflicts of interest can be found with very little digging in Australia

Experts believe lobeline, the active ingredient in the lobelia plant, works by binding to the same receptor sites in the brain as nicotine