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Since nicotine is considered an incredibly addictive substance, it can be difficult for many to refrain from putting a cigarette to their lips, even if someone wholly understands the detrimental health consequences

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Additionally, it further promotes vascular thrombosis by facilitating the cleavage of the fibrin zymogen (fibrinogen), as well as by activating factor XI, preventing fibrinolysis, and factor XIII, which further stabilizes the fibrin clot