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The absence of a longitudinal follow-up limits the ability to track the progression of OSMF and other oral lesions over time, establish temporal relationships between risk factors (e.g., areca nut use) and lesion development and assess outcomes such as lesion regression or malignant transformation

In the UK, nicotine containing e-liquids have a maximum nicotine strength of 20 mg/ml (2%), so this is the highest strength you will be able to find

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Factors Affecting Prognosis Smoking cessation represents the most significant modifiable factor influencing survival rates