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Out-of-Pocket Cost per Smoker $137,357 (Rank: 45th) Financial-Opportunity Cost per Smoker $2,328,466 (Rank: 45th) Health-Care Cost per Smoker $147,698 (Rank: 45th) Income Loss per Smoker $616,507 (Rank: 29th) Other Costs per Smoker $15,319 (Rank: 34th) Total Cost Over Lifetime per Smoker: $3,245,347 Total Cost per Year per Smoker: $67,611 Significant public health issue The backstory: Smoking remains a significant public health issue in the United States

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Of these genes, it is interesting that FOXJ1, which stimulates ciliogenesis 29 was significantly downregulated after LC exposure, which is consistent with the deciliation seen in Fig