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And in both men and women, researchers found around a 30 percent increase in the risk of stroke

Children who are younger than 3 years old account for most liquid nicotine exposures

Treating Opioid Use Disorder During Pregnancy Opioid withdrawal during pregnancy increases the risk of return to opioid use without benefit to mother or baby

The working group also used GRADE to determine the certainty of the evidence and strength of the recommendation (Box 1).21 Appendices 47 (available at www.cmaj.ca/lookup/doi/10.1503/cmaj.241584/tab-related-content) provide the evidence-to-decision frameworks the task force used to develop recommendations

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