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These results suggest that both low and high copper levels induce oxidative stress, with HepG2 ATP7B-KO cells being more sensitive under physiological copper conditions

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The authors hypothesised that xCT inhibition might be further potentiated by limiting glutamate or glutamine availability, and show that xCT is a compelling therapeutic target for triple-negative tumours

Silver sulphadiazine-induced hemolytic anemia in a glucose-6-phosphate dehydrogenase-deficient burn patient