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Analyses by Public Health England, the American National Academies of Sciences, Engineering, and Medicine and the British Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment all show that aerosols from e-cigarettes contain a much smaller number and amount of toxic substances than cigarette smoke and are therefore less harmful to health than smoked tobacco

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A previous meta-analysis in 2016, conducted by some of the same authors behind the 2020 study, found that graphic images were more effective at preventing smoking or getting smokers to quit than text warnings.