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Tobacco dust = Shafer's sign Ahmed Omara "Tobacco dust," or Shafers sign, refers to the presence of fine brown pigmented cells (from the retinal pigment epithelium) floating in the anterior vitreous. , Its an important clinical clue Schaffer sign Tobacco dust sign Pigments in anterior Vitreous Flashes and floaters in community optometry diagnosing a posterior vitreous detachment Eye News Pleural effusion in an immunocompetent host with cryptococcal pneumonia: A case report
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