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Among the four regions defined here, the South has the second highest prevalence of smoking, but it contains three of the six states where smoking is the most prevalent (Kaiser Family Foundation 2006)

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It is well known that when some VOCs are combined, secondary pollutants such as formaldehyde (a known nose, throat, and lung irritant) may be produced

The toxic dose of nicotine for adults is around 50-60 mg, but nicotine poisoning can start at much lower levels, especially in individuals who have a lower tolerance or are new to nicotine use