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Device considerations Premixed closed systems are recommended to avoid the following risks: inappropriate or incorrect dilution of liquid nicotine (the dilution process is not straightforward and relies on adequate product labelling) intentional or accidental ingestion or exposure through skin or eyes addition of potentially toxic or illegal substances, or contamination Therapeutic guidelines on nicotine toxicity state the potentially lethal oral exposure dose is 5 mg/kg

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As a veteran of the airline industry, l've seen this industry go through many seasons, but the support from our fellow aviators at other carriers is what makes this community so special

Cotinine : A metabolite of nicotine produced by the liver and excreted through the kidneys, used to measure nicotine intake