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Limitations of current research include the following: Although many of these limitations are difficult to eliminate, there are ways to improve clinical research in this space by utilizing newer neuropsychological assessment tools that assess a greater breadth of neurocognitive domains, offer high accuracy and reliability, and produce more granular data

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federal government agencies, have demonstrated that using reduced nicotine content tobacco cigarettes like VLN helps smokers reduce their nicotine exposure and dependence, smoke fewer cigarettes per day, increase their number of smoke-free days, and double their quit attempts all with minimal or no nicotine withdrawal symptoms or compensatory smoking behavior