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"The results of this study support health warnings that there is no safe level of exposure to tobacco smoke," the study's lead author says in a National Institutes of Health news release

"Both smoking and HPV are associated with heightened oxidative stress and DNA damage, which are factors in cancer, and according to previous research, can regulate superoxide dismutase 2 [SOD2], a putative biomarker of oral cancer malignancy and other diseases associated with HPV." The researchers began by analyzing oral cells that contained the oncoproteins HPV16 E6 and E7 [indicating HPV infection] and were exposed to cigarette smoke condensate in vitro

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This inflammation weakens the arterial walls, making them more susceptible to the buildup of fatty deposits (atherosclerosis)

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