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For the time and limitations involved, these were quite interesting and must have been difficult to fill

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For the coat protein CDS, a less conserved profile was observed, with a typical length of 828 bases (276 amino acids) and the presence of gaps in the alignment and significant variations, especially at the 5 regions of the CDSs

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In line with this, it has been observed that cigarette smoke induces the release of TNF- in an in vitro macrophage model system 56 , but others found no increased release of TNF- peripheral blood mononuclear cells to cigarette smoke extracts 57