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There are both clinical [115,116,117] and experimental [116, 118,119,120] data supporting an association between disrupted pulmonary iron homeostasis, leading to accumulation of iron in cells or airway tissue, and asthma

Workers in coke oven plants have a higher incidence of lung cancer than the general population and a measurable concentration of PAHs in urine, which is higher in smokers than non-smokers (Haugen et al., 1986)

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