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This finding suggests that women who smoke are more likely to develop the unhealthy apple shape typically associated with men

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Because clinical trials are conducted under widely varying conditions, the adverse reactions rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice

Photo: Karlamalie via Wikimedia Commons (Public Domain) What to Look For: Shape: Round with spiky protrusions (looks like a naval mine or a pollen grain)

Generalizability may have been further limited due to the narrow focus on data from European patients