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Methods Mean concentrations and the area under the curve of PM 10 , PM 2.5 and PM 1 generated by Natural American Spirit cigarettes without additives and the 3R4F standard research cigarette (University of Kentucky, USA) were measured, analyzed and compared with each other

Although the accumulation of lipids in the liver of treated animals could indicate the development of liver steatosis or NAFLD, further work focused on these diseases are needed to elucidate all the morphophysiological alterations that occur during the development of these diseases

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