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With an array of novel tobacco products reaching the market, there is an opportunity to make key distinctions between cigarettes and smoke free products

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After 1964, when the Surgeon Generals office released its authoritative report on the adverse effects of cigarette smoking, the increase in smoking slowed, stopped, and eventually reversed in the United States

In our study, the smoking regime used to generate emissions from IQOS was the HCI regime used for conventional cigarettes