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Milky-white toxin contains bufadienolides, which are cardiac glycosides, tryptamines (e.g., bufotenine, 5-MeO-DMT), various catecholamines such as epinephrine and norepinephrine, and non-cardioactive sterols (Erspamer et al., 1967

But prohibitionist groups are also lobbying hard. Xander Shepherd, co-founder of THC aperitif brand Artet (his 86-year-old grandmothers art adorns the bottles), says that flux in this sector is nothing new: Ive almost become numb to the constant changes, whether its the Farm Bill or state-level regulations

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My husband and I were recently lucky enough to take a (kid-free!) trip to Asheville, NC

Costigan S, Meredith C